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Article

Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors.

BMC cancer - 7 Jan 2009

Chosdol Kunzang, Misra Anjan, Puri Sachin, Srivastava Tapasya, Chattopadhyay Parthaprasad, Sarkar Chitra, Mahapatra Ashok K, Sinha Subrata

Abstract excerpt

BACKGROUND: We had earlier used the comparison of RAPD (Random Amplification of Polymorphic DNA) DNA fingerprinting profiles of tumor and corresponding normal DNA to identify genetic alterations in primary human glial tumors. This has the advantage that DNA fingerprinting identifies the genetic alterations in a manner not biased for locus. METHODS: In this study we used RAPD-PCR to identify novel genomic...

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Identifiers

PMID: 19126244
DOI: 10.1186/1471-2407-9-5
PMCID: PMC2631005

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Source receipt: pubmed, retrieved 7 Sept 2026.

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