Article
Pathogenicity of a mutant friend spleen focus-forming virus encoding an Env-like membrane glycoprotein (gp55) with substitution by a xenotropic murine leukemia virus Env gp70 sequence.
Microbiology and immunology - 1 Jan 1998
Yugawa T, Amanuma H
Abstract excerpt
Friend spleen focus-forming virus (F-SFFV) is a replication-defective acutely leukemogenic mouse retrovirus and encodes an envelope protein (Env)-like membrane glycoprotein (gp55) in its defective env gene, which is responsible for the early stage of the viral leukemogenesis. Gp55 is a modified E...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Binding, Competitive
- Cells, Cultured
- Genes, env
- Leukemia Virus, Murine
- Mice
- Mice, Inbred DBA
- Molecular Sequence Data
- Mutation
- Receptors, Virus
- Retroviridae Proteins, Oncogenic
- Spleen Focus-Forming Viruses
- Structure-Activity Relationship
- Transfection
- Viral Envelope Proteins