Article
A carboxy-terminal mutant spleen focus-forming virus (SFFV) envelope glycoprotein is transport-competent, but non-leukemogenic.
Virus research - 1 Oct 1992
Srinivas R V, Rui Z, Compans R W
Abstract excerpt
The Friend spleen focus-forming virus (F-SFFV) codes for a transport-defective leukemogenic envelope glycoprotein designated as gp52. We have previously shown that the external domain of gp52 carries the determinants responsible for its transport defect. Consistent with this idea, truncated gp52...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Transport
- Cell Line
- Genes, env
- Leukemia, Erythroblastic, Acute
- Mice
- Molecular Sequence Data
- Molecular Weight
- Moloney murine leukemia virus
- Mutation
- Spleen Focus-Forming Viruses
- Viral Envelope Proteins