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Article

A 585-bp deletion found in the spleen focus-forming virus (SFFV) env gene is responsible for the defective intracellular transport of SFFV gp52.

Virology - 1 May 1992

Srinivas R V, Tucker S P, Kilpatrick D R, Compans R W

Abstract excerpt

The Friend spleen focus-forming virus (F-SFFV) codes for a transport defective, leukemogenic envelope glycoprotein designated as gp52. Gp52 closely resembles the envelope glycoproteins (gp70-p15E) encoded by the mink cell focus-forming viruses (MCFV). The major differences between SFFV and MCFV include a 585-bp deletion and a frame-shift mutation near the 3' end of the SFFV env gene. We have constructed a mutant...

Topics

3T3 Cells
Animals
Biological Transport
Carrier Proteins
Cell Membrane
Cell Transformation, Neoplastic
Cell Transformation, Viral
Disulfides
Endoplasmic Reticulum Chaperone BiP
Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, env

Glycoproteins

Heat-Shock Proteins

Mice

Mink Cell Focus-Inducing Viruses

Molecular Chaperones

Mutation

Spleen Focus-Forming Viruses

Source

Identifiers

PMID: 1566572
DOI: 10.1016/0042-6822(92)90748-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1566572-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A 585-bp deletion found in the spleen focus-forming virus (SFFV) env gene is responsible for the defective intracellular transport of SFFV gp52.PMID 1566572Read ↗

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