Article
Characterization of the cutaneous exanthem in macaques infected with a Nef gene variant of SIVmac239.
The Journal of investigative dermatology - 1 Jun 1998
Sasseville V G, Rottman J B, Du Z, Veazey R, Knight H L, Caunt D, Desrosiers R C, Lackner A A
Abstract excerpt
The molecularly cloned viruses known as SIVmac239/R17Y and SIVmac239/YEnef cause extensive lymphocyte activation and induce an acute disease syndrome in macaque monkeys. One manifestation of this syndrome is a severe diffuse cutaneous maculopapular exanthem that is similar to the exanthem associated with HIV-1 infection. To examine the pathogenesis of this exanthem, biopsies obtained throughout the course of...
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