Article
Characterization of the cutaneous exanthem in macaques infected with a Nef gene variant of SIVmac239.
The Journal of investigative dermatology - 1 Jun 1998
Sasseville V G, Rottman J B, Du Z, Veazey R, Knight H L, Caunt D, Desrosiers R C, Lackner A A
Abstract excerpt
The molecularly cloned viruses known as SIVmac239/R17Y and SIVmac239/YEnef cause extensive lymphocyte activation and induce an acute disease syndrome in macaque monkeys. One manifestation of this syndrome is a severe diffuse cutaneous maculopapular exanthem that is similar to the exanthem associa...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Neoplasm
- Biopsy
- Blood Vessels
- CD8-Positive T-Lymphocytes
- Cell Division
- E-Selectin
- Exanthema
- Genes, Viral
- Genes, nef
- Genetic Variation
- HIV Infections
- Immunohistochemistry
- Integrins
- Ki-67 Antigen
- Leukocyte Count
- Lymphocyte Count