Article
Association between catechol O-methyltransferase genotype and violence in schizophrenia and schizoaffective disorder.
The American journal of psychiatry - 1 Jun 1998
Lachman H M, Nolan K A, Mohr P, Saito T, Volavka J
Abstract excerpt
OBJECTIVE: The authors previously reported a relationship between an allele encoding the low activity variant of catechol O-methyltransferase (COMT) and aggressive behavior in schizophrenic patients. This study replicates and extends these findings by using more direct measures of violent behavior. METHOD: Fifty-five white patients (34 men, 21 women) with DSM-IV diagnoses of schizophrenia or schizoaffective...
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