Article
Effect of COMT genotype on aggressive behaviour in a community cohort of schizophrenic patients.
Neuroscience letters - 9 May 2011
Tosato Sarah, Bonetto Chiara, Di Forti Marta, Collier David, Cristofalo Doriana, Bertani Mariaelena, Zanoni Martina, Marrella Giovanna, Lazzarotto Lorenza, Lasalvia Antonio, De Gironcoli Marzia, Tansella Michele, Dazzan Paola, Murray Robin, Ruggeri Mirella
Abstract excerpt
Although the etiology of aggression is multifactorial, many studies have associated the Val158Met polymorphism of the COMT with aggression in schizophrenia. This study tests the hypothesis that Met/Met patients display more episodes of aggression and violent behaviour than Val/Val patients in a 6 year follow-up cohort of subjects with schizophrenia in contact with the South-Verona Community-based Mental Health...
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