Article
The COMT Met158 allele and violence in schizophrenia: a meta-analysis.
Schizophrenia research - 1 Sept 2012
Bhakta Savita G, Zhang Jian-Ping, Malhotra Anil K
Abstract excerpt
BACKGROUND: The Met158 allele of catechol-O-methyl transferase (COMT) gene is associated with increased levels of catecholamines in the prefrontal cortex and may increase the likelihood of aggressiveness. We conducted a meta-analysis to test the hypothesis that the Met158 allele of the COMT gene is associated with aggressive and violent behavior in schizophrenia. METHODS: MEDLINE search (12/31/11) yielded 14...
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