Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An in vitro model to study mesenchymal-epithelial transformation.

Biochemical and biophysical research communications - 29 May 1998

Ouyang P

Abstract excerpt

Mesenchymal-epithelial transformation (MET) is an important process in the embryogenesis of organisms. In an attempt to study the mechanism of MET, we present here the identification of a cloned human chondrosarcoma cell line, the SW1353, that is capable of converting to cells with an obvious epithelial phenotype. The transformation of the fibroblast-like SW1353 cells to epithelial cells occurred in a defined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Epithelial Cells
Share to Fibroblasts

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mesoderm

Share to Models, Biological

Share to Phenotype

Share to Proto-Oncogene Mas

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9618287
DOI: 10.1006/bbrc.1998.8710

Genes

MET
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An in vitro model to study mesenchymal-epithelial transformation.PMID 9618287Read ↗

Genetically transforming human mesenchymal stem cells to sarcomas: changes in cellular phenotype and multilineage differentiation potential.Semantic proximity Read ↗

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation.Semantic proximity Read ↗

Rat bone marrow mesenchymal stem cells undergo malignant transformation via indirect co-cultured with tumour cells.Semantic proximity Read ↗

Establishment and Characterization of a Continuous Human Chondrosarcoma Cell Line, ch-2879: Comparative Histologic and Genetic Studies with Its Tumor of OriginSemantic proximity Read ↗

Epithelial-to-mesenchymal change of differentiation. From embryogenetic mechanism to pathological patterns.Semantic proximity Read ↗

Towards a new understanding and classification of chondrogenic neoplasias of the skeleton--biochemistry and cell biology of chondrosarcoma and its variants.Semantic proximity Read ↗

A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation.Semantic proximity Read ↗

A novel mutated cell line with characteristics of dedifferentiated chondrosarcoma.Semantic proximity Read ↗

A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcomaSemantic proximity Read ↗

The functions of HGF/SF and its receptor, the c-Met tyrosine kinase, in mammalian development.Semantic proximity Read ↗

Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells.Semantic proximity Read ↗

c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.