Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells.

Oncogene - 15 Aug 1996

Jeffers M, Rong S, Anver M, Vande Woude G F

Abstract excerpt

Hepatocyte growth factor/scatter factor (HGF/SF) is a pleiotropic effector of cells expressing the Met tyrosine kinase receptor. C127 is a non-tumorigenic mouse cell line which expresses negligible levels of HGF/SF and Met proteins. In the present report we have generated C127 cells which overexpress HGF/SF and/or Met proteins, and have analysed the effect of HGF/SF-Met signaling in these cells. We show that this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Neoplasm Metastasis

Share to Phenotype

Share to Receptor Protein-Tyrosine Kinases

Share to Signal Transduction

Source

Identifiers

PMID: 8761307

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells.PMID 8761307Read ↗

The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review).Semantic proximity Read ↗

Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation.Semantic proximity Read ↗

Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.Semantic proximity Read ↗

MET: a critical player in tumorigenesis and therapeutic target.Semantic proximity Read ↗

c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.Semantic proximity Read ↗

C-Met Autocrine Activation Induces Development Of Malignant Melanoma And Acquisition Of The Metastatic PhenotypeSemantic proximity Read ↗

Hepatocyte growth factor/scatter factor-induced intracellular signalling.Semantic proximity Read ↗

Hepatocyte growth factor/scatter factor—Met signaling in tumorigenicity and invasion/metastasisSemantic proximity Read ↗

Involvement of HGF/SF-Met signaling in prostate adenocarcinoma cells: evidence for alternative mechanisms leading to a metastatic phenotype in Pr-14c.Semantic proximity Read ↗

Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinaseSemantic proximity Read ↗

HGF/SF-Met signaling in tumor progression.Semantic proximity Read ↗

Tumorigenicity of the <i>met</i> Proto-Oncogene and the Gene for Hepatocyte Growth FactorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.