Article
A novel mutated cell line with characteristics of dedifferentiated chondrosarcoma.
International journal of molecular medicine - 1 Oct 2009
Yang Liye, Chen Qiang, Zhang Song, Wang Xianyao, Li Wenyu, Wen Jiancheng, Huang Xiaoping, Zheng Jiakun, Huang Ge, Huang Tianhua, Ju Guizhi
Abstract excerpt
Dedifferentiated chondrosarcoma (CS) is a rare, highly malignant variant of CS in which a high-grade sarcoma coexists with a low-grade chondroid tumor. In this study, a novel dedifferentiated CS cell line, MS0812, was spontaneously established from mutated human embryonic muscle cells. Several features of the cell line were investigated, including growth characteristics, cytogenetics, electron microscopic...
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