Epithelial-to-mesenchymal change of differentiation. From embryogenetic mechanism to pathological patterns.

Abstract excerpt

In embryonic morphogenesis, dramatic changes from one state of differentiation to another take place, and some epithelia transform into mesenchymal cells endowed with the ability to migrate and to form connective tissue. In vitro model systems have been developed which have provided new insights into crucial aspects of this differentiation change. Triggered perhaps by either extracellular matrix or growth...

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