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Article

Rat bone marrow mesenchymal stem cells undergo malignant transformation via indirect co-cultured with tumour cells.

Cell biochemistry and function - 1 Dec 2012

Liu Jianping, Zhang Yalan, Bai Lu, Cui Xiangrong, Zhu Jing

Abstract excerpt

Mesenchymal stem cells (MSCs) have potential applications in regenerative medicine and tissue engineering as well as being potential carriers for tumour therapy. However, the safety of using MSCs in tumours is unknown. Herein, we analyse malignant transformation of MSCs in the tumour microenvironment. Rat bone marrow MSCs were cultured with malignant rat glioma C6 cells without direct cell-cell contact. After...

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Source

Identifiers

PMID: 22763674
DOI: 10.1002/cbf.2844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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