Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of butyrate analogues on proliferation and differentiation in human neuroblastoma cell lines.

Anticancer research - 1 Jan 2000

Rocchi P, Ferreri A M, Magrini E, Perocco P

Abstract excerpt

Butyric acid has been shown in vitro to produce cytodifferentiation of a wide variety of neoplastic cells. The potential clinical use of this compound as a therapeutic agent is limited by its rapid metabolism. This has led to the examination, as potential antineoplastic agents, of compounds structurally correlated to butyrate, with longer biological half lives. In this study we investigated the effect in vitro of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amides
Share to Cell Differentiation
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neuroblastoma

Share to Phenotype

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9615772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of butyrate analogues on proliferation and differentiation in human neuroblastoma cell lines.PMID 9615772Read ↗

Tributyrin, an oral butyrate analogue, induces apoptosis through the activation of caspase-3.Semantic proximity Read ↗

Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma.Semantic proximity Read ↗

In vitro phenotypic alteration of human melanoma cells induced by differentiating agents: heterogeneous effects on cellular growth and morphology, enzymatic activity, and antigenic expression.Semantic proximity Read ↗

Tribromophenol induces the differentiation of SH-SY5Y human neuroblastoma cells in vitroSemantic proximity Read ↗

Characterization of sublines of HL-60 human leukemia cells resistant to induction of differentiation by butyric acid.Semantic proximity Read ↗

Effects of 1,25-dihydroxyvitamin D3 and its analogs on butyrate-induced differentiation of HT-29 human colonic carcinoma cells and on the reversal of the differentiated phenotype.Semantic proximity Read ↗

Inhibition of proliferation and induction of differentiation in medulloblastoma- and astrocytoma-derived cell lines with phenylacetate.Semantic proximity Read ↗

Modulation of cell cycle-related protein expression by sodium butyrate in human non-small cell lung cancer cell lines.Semantic proximity Read ↗

Inhibition of anchorage-independent growth of tumor cells by IT-62-B, a new anthracycline.Semantic proximity Read ↗

Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP.Semantic proximity Read ↗

Up-regulation of E-cadherin and I-catenin in human hepatocellular carcinoma cell lines by sodium butyrate and interferon-alpha.Semantic proximity Read ↗

Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.