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Article

Adenovirus-mediated interleukin-2 production by tumors induces growth of cytotoxic tumor-infiltrating lymphocytes against human renal cell carcinoma.

Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 May 1998

Mulders P, Tso C L, Pang S, Kaboo R, McBride W H, Hinkel A, Gitlitz B, Dannull J, Figlin R, Belldegrun A

Abstract excerpt

Combination therapy with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes (TILs) demonstrates significant clinical activity in patients with metastatic renal cell carcinoma (RCC). To investigate whether local delivery of IL-2 via gene transfer is capable of improving the potency and efficacy of in vitro propagated TILs as compared with standard growth conditions [400 BRMP U (BU)/ml], a...

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Identifiers

PMID: 9610908
DOI: 10.1097/00002371-199805000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Adenovirus-mediated interleukin-2 production by tumors induces growth of cytotoxic tumor-infiltrating lymphocytes against human renal cell carcinoma.PMID 9610908Read ↗

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