Article
[Adoptive immunotherapy and metastasized cancer of the kidney. Regulator effects of interleukin-4 on tumor infiltrating lymphocytes (TIL)].
Chirurgie; memoires de l'Academie de chirurgie - 1 Jan 1991
Peyret C, Bochner B, Lee T Y, Tso C L, Dekernion J B, Belldegrun A
Abstract excerpt
Adoptive immunotherapy is a new therapeutic approach of the treatment of advanced renal cell cancer. Experimental studies have shown that the cells with the highest cytolytic activity are tumor infiltrating lymphocytes (TIL). The effects of interleukin-4 (IL-4) on the expansion, proliferation, phenotype and antitumor activity of TIL were studied. Cultures were obtained from three primary renal tumors and one...
Topics
- Adenocarcinoma
- Humans
- Immunotherapy, Adoptive
- Interleukin-2
- Interleukin-4
- Kidney Neoplasms
- Killer Cells, Lymphokine-Activated
- Lymphocyte Subsets
- Lymphocytes, Tumor-Infiltrating
- Neoplasm Metastasis
