Article
Continuity in evolution: on the nature of transitions.
Science (New York, N.Y.) - 29 May 1998
Fontana W, Schuster P
Abstract excerpt
To distinguish continuous from discontinuous evolutionary change, a relation of nearness between phenotypes is needed. Such a relation is based on the probability of one phenotype being accessible from another through changes in the genotype. This nearness relation is exemplified by calculating the shape neighborhood of a transfer RNA secondary structure and provides a characterization of discontinuous shape...
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