Insertions and deletions in the RNA sequence-structure map.

Abstract excerpt

Genotype-phenotype maps link genetic changes to their fitness effect and are thus an essential component of evolutionary models. The map between RNA sequences and their secondary structures is a key example and has applications in functional RNA evolution. For this map, the structural effect of substitutions is well understood, but models usually assume a constant sequence length and do not consider insertions or...

Topics

• Base Sequence
• Evolution, Molecular
• Genotype
• INDEL Mutation
• Models, Genetic
• Mutation
• RNA