Article
Multiplicity of phenotypes and RNA evolution.
Journal of theoretical biology - 14 Jun 2018
Rezazadegan Reza, Barrett Chris, Reidys Christian
Abstract excerpt
Motivation Motoo Kimura's neutral theory stipulates that evolution is predominantly driven by neutral mutations. RNA, realizing both genotype (its linear sequence of nucleotides) as well as phenotype (its folded secondary structure) represents a particularly well suited test bed for studying neutrality. This leads to neutral networks of RNA secondary structures, i.e. sets of sequences all of which folding into a...
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