Article
Exploring phenotype space through neutral evolution.
Journal of molecular evolution - 1 Sept 1996
Huynen M A
Abstract excerpt
RNA secondary-structure folding algorithms predict the existence of connected networks of RNA sequences with identical secondary structures. Fitness landscapes that are based on the mapping between RNA sequence and RNA secondary structure hence have many neutral paths. A neutral walk on these fitness landscapes gives access to a virtually unlimited number of secondary structures that are a single point mutation...
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