Article
Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin.
Journal of molecular biology - 8 May 1998
Levashina E A, Ohresser S, Lemaitre B, Imler J L
Abstract excerpt
Metchnikowin is a recently discovered proline-rich peptide from Drosophila with antibacterial and antifungal properties. Like most other antimicrobial peptides from insects, its expression is immune-inducible. Here we present evidence that induction of metchnikowin gene expression can be mediated...
Topics
- Animals
- Animals, Genetically Modified
- Anti-Infective Agents
- Antimicrobial Cationic Peptides
- Base Sequence
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation
- Genes, Insect
- Genes, Reporter
- Glycopeptides
- Insect Proteins
- Larva
- Molecular Sequence Data
- Mutation
- Peptides
- Promoter Regions, Genetic