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Article

Effect of vitamin D receptor gene alleles on bone loss in early rheumatoid arthritis.

The Journal of rheumatology - 1 May 1998

Gough A, Sambrook P, Devlin J, Lilley J, Huisoon A, Betteridge J, Franklyn J, Nguyen T, Morrison N, Eisman J, Emery P

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is a polygenic disease characterized by localized joint destruction and generalized osteoporosis resulting in increased fracture risk. The pathogenetic mechanisms that determine the severity of generalized bone loss in RA are poorly understood. Polymorphisms in the vitamin D receptor (VDR) gene have been described as a significant determinant of bone turnover and mass. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9598881

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Effect of vitamin D receptor gene alleles on bone loss in early rheumatoid arthritis.PMID 9598881Read ↗

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