Article
Vitamin D receptor gene polymorphism in rheumatoid arthritis and associated osteoporosis.
Rheumatology international - 1 Sept 2006
Rass Péter, Pákozdi Angéla, Lakatos Péter, Zilahi Erika, Sipka Sándor, Szegedi Gyula, Szekanecz Zoltán
Abstract excerpt
Rheumatoid arthritis (RA) is commonly associated with decreased bone mineral density (BMD) due to numerous factors. BsmI polymorphism of the vitamin D receptor (VDR) gene has been implicated in the pathogenesis of osteoporosis. Vitamin D has several immunomodulatory effects and thus may play a role in the course of arthritis. However, little data is available on the possible relationship between RA and VDR gene...
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