Article
Vitamin D receptor genotypes are not associated with rheumatoid arthritis or biochemical parameters of bone turnover in German RA patients.
Clinical and experimental rheumatology - 1 Jan 2000
Goertz B, Fassbender W J, Williams J C, Marzeion A M, Bretzel R G, Stracke H, Berliner M N
Abstract excerpt
OBJECTIVE: Vitamin D is known to exert immunomodulatory effects. An overrepresentation of the b allele of the vitamin D receptor (VDR) has been detected in autoimmune diseases as type-1-diabetes and multiple sclerosis. VDR polymorphisms have been shown to influence bone metabolism and bone density. The aim of the present study was to examine the distribution of VDR alleles in German rheumatoid arthritis (RA)...
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