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Article

Allelic variation at the interleukin-1 receptor antagonist gene is associated with early postmenopausal bone loss at the spine.

Bone - 1 Oct 1998

Keen R W, Woodford-Richens K L, Lanchbury J S, Spector T D

Abstract excerpt

Genetic factors play an important role in determining bone mineral density (BMD) in later life, with the genetic influence mediated through effects on both peak mass and on age- and menopause-related bone loss. At menopause there is an increase in the production and activity of various cytokines and growth factors within the bone microenvironment. The activity of interleukin-1 (IL-1), a powerful stimulant of...

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Source

Identifiers

PMID: 9763149
DOI: 10.1016/s8756-3282(98)00109-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allelic variation at the interleukin-1 receptor antagonist gene is associated with early postmenopausal bone loss at the spine.PMID 9763149Read ↗

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