Article
Influence of the BsmI polymorphism of the vitamin D receptor gene on rheumatoid arthritis clinical activity.
The Journal of rheumatology - 1 Sept 2007
Gómez-Vaquero Carmen, Fiter Jordi, Enjuanes Ana, Nogués Xavier, Díez-Pérez Adolfo, Nolla Joan M
Abstract excerpt
OBJECTIVE: The etiopathogenesis of rheumatoid arthritis (RA) is not fully known; vitamin D has been shown to have immunomodulatory effects and could be implicated in it. BsmI polymorphism of vitamin D receptor (VDR) gene is involved in the pathogenesis of osteoporosis in RA. We analyzed the effect of this polymorphism on clinical activity in 123 Spanish postmenopausal women with RA. METHODS: Patients with RA were...
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