Article
Genetics of bone loss in rheumatoid arthritis--role of vitamin D receptor polymorphisms.
Rheumatology (Oxford, England) - 1 Apr 2009
Ranganathan P
Abstract excerpt
RA is a systemic inflammatory arthritis that leads to local and systemic bone loss. Osteoporosis or the systemic bone loss associated with RA increases the risk for fragility fractures, which can affect quality of life dramatically in RA patients. Although traditional and RA-related risk factors have been defined and studied for osteoporosis associated with RA, genetic factors such as polymorphic variants in the...
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