Article
Frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae in Tokyo in 2002.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Dec 2003
Abe Hiroyuki, Nishimura Taiji, Norose Yoshihiko, Aoto Taiji, Ohzuka Hiroki, Ohkuni Hisashi
Abstract excerpt
The frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae obtained in Tokyo in 2002 was studied. The frequencies of GyrA and ParC mutations in these 19 isolates were 100% (19 of 19) and 84.2% (16 of 19), respectively, and these results were 1.48-fold (100%/67.6%) and 3.58-fold (84.2%/23.5%) higher, respectively, than...
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