Article
Genetic mapping of a locus (mass1) causing audiogenic seizures in mice.
Genomics - 15 Apr 1998
Skradski S L, White H S, Ptácek L J
Abstract excerpt
Frings audiogenic seizure-susceptible mice are a model for sensory-evoked reflex seizures. Their seizure phenotype is characterized by wild running, loss of righting reflex, tonic flexion, and tonic extension in response to high-intensity sound stimulation. The Frings mice represent an inbred col...
Topics
- Acoustic Stimulation
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Disease Models, Animal
- Disease Susceptibility
- Female
- Genetic Linkage
- Genotype
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Microsatellite Repeats
- Seizures