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Article

Generation and Characterization of Three Novel Mouse Mutant Strains Susceptible to Audiogenic Seizures.

Cells - 22 Oct 2024

Varlamova Elena G, Kuldaeva Vera P, Mitina Natalia N, Gavrish Maria S, Kondakova Elena V, Tarabykin Victor S, Babaev Alexei A, Turovsky Egor A

Abstract excerpt

The mechanisms of epileptogenesis after brain injury, ischemic stroke, or brain tumors have been extensively studied. As a result, many effective antiseizure drugs have been developed. However, there are still many patients who are resistant to therapy. The molecular and genetic bases regarding such drug-resistant seizures have been poorly elucidated. In many cases, heavy seizures are instigated by brain...

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Identifiers

PMID: 39513854
DOI: 10.3390/cells13211747
PMCID: PMC11545774

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