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Article

Audiogenic seizure proneness requires the contribution of two susceptibility loci in mice.

Neurogenetics - 1 Aug 2011

Jawahar M Catharine, Sari Carolina I, Wilson Yvette M, Lawrence Andrew J, Brodnicki Thomas, Murphy Mark

Abstract excerpt

Juvenile mice of the DBA/2J strain undergo generalised seizures when exposed to a high-intensity auditory stimulus. Genetic analysis identified three different loci underlying this audiogenic seizure proneness (ASP)-Asp1, Asp2 and Asp3 on chromosomes 12, 4 and 7, respectively. Asp1 is thought to have the strongest influence, and mice with only Asp1 derived from the DBA/2J strain are reported to exhibit ASP. The...

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Identifiers

PMID: 21681693
DOI: 10.1007/s10048-011-0289-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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