Article
LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells.
Infection and immunity - 1 Jun 1998
Sarker M R, Sory M P, Boyd A P, Iriarte M, Cornelis G R
Abstract excerpt
Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors.
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