Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of the Yersinia pestis type III regulatory proteins LcrG and LcrV occurs at a hydrophobic interface.

BMC microbiology - 28 Jun 2002

Matson Jyl S, Nilles Matthew L

Abstract excerpt

BACKGROUND: Secretion of anti-host proteins by Yersinia pestis via a type III mechanism is not constitutive. The process is tightly regulated and secretion occurs only after an appropriate signal is received. The interaction of LcrG and LcrV has been demonstrated to play a pivotal role in secretion control. Previous work has shown that when LcrG is incapable of interacting with LcrV, secretion of anti-host...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Hydrophobic and Hydrophilic Interactions
Share to Leucine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenylalanine

Share to Plague

Share to Pore Forming Cytotoxic Proteins

Share to Protein Interaction Mapping

Share to Yersinia pestis

Source

Open in PubMed Open full text

Identifiers

PMID: 12102728
DOI: 10.1186/1471-2180-2-16
PMCID: PMC117220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of the Yersinia pestis type III regulatory proteins LcrG and LcrV occurs at a hydrophobic interface.PMID 12102728Read ↗

LcrG-LcrV interaction is required for control of Yops secretion in Yersinia pestis.Semantic proximity Read ↗

The V antigen of Yersinia pestis regulates Yop vectorial targeting as well as Yop secretion through effects on YopB and LcrG.Semantic proximity Read ↗

Roles of LcrG and LcrV during type III targeting of effector Yops by Yersinia enterocolitica.Semantic proximity Read ↗

Roles of YopN, LcrG and LcrV in controlling Yops secretion by Yersinia pestis.Semantic proximity Read ↗

Diminished LcrV secretion attenuates Yersinia pseudotuberculosis virulence.Semantic proximity Read ↗

LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells.Semantic proximity Read ↗

Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis.Semantic proximity Read ↗

The V-antigen of Yersinia is surface exposed before target cell contact and involved in virulence protein translocation.Semantic proximity Read ↗

The type III secretion chaperone LcrH co-operates with YopD to establish a negative, regulatory loop for control of Yop synthesis in Yersinia pseudotuberculosis.Semantic proximity Read ↗

YopD self-assembly and binding to LcrV facilitate type III secretion activity by Yersinia pseudotuberculosis.Semantic proximity Read ↗

lcrR, a low-Ca2(+)-response locus with dual Ca2(+)-dependent functions in Yersinia pestis.Semantic proximity Read ↗

LcrH, a class II chaperone from the type three secretion system, has a highly flexible native structure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.