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Article

Neither the Bvg- phase nor the vrg6 locus of Bordetella pertussis is required for respiratory infection in mice.

Infection and immunity - 1 Jun 1998

Martinez de Tejada G, Cotter P A, Heininger U, Camilli A, Akerley B J, Mekalanos J J, Miller J F

Abstract excerpt

In Bordetella species, the BvgAS sensory transduction system mediates an alteration between the Bvg+ phase, characterized by expression of adhesins and toxins, and the Bvg- phase, characterized by the expression of motility and coregulated phenotypes in Bordetella bronchiseptica and by the expression of vrg loci in Bordetella pertussis. Since there is no known environmental or animal reservoir for B. pertussis,...

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Identifiers

PMID: 9596745
DOI: 10.1128/IAI.66.6.2762-2768.1998
PMCID: PMC108267

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Neither the Bvg- phase nor the vrg6 locus of Bordetella pertussis is required for respiratory infection in mice.PMID 9596745Read ↗

Genetic regulation of airway colonization by Bordetella species.Semantic proximity Read ↗

Identification and genomic organization of gene loci negatively controlled by the virulence regulatory BvgAS two-component system in Bordetella bronchiseptica.Semantic proximity Read ↗

Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine.Semantic proximity Read ↗

A mutation in the Bordetella bronchiseptica bvgS gene results in reduced virulence and increased resistance to starvation, and identifies a new class of Bvg-regulated antigens.Semantic proximity Read ↗

Comparative analysis of the virulence control systems of Bordetella pertussis and Bordetella bronchiseptica.Semantic proximity Read ↗

BvgAS-mediated signal transduction: analysis of phase-locked regulatory mutants of Bordetella bronchiseptica in a rabbit model.Semantic proximity Read ↗

Evaluation of the role of the Bvg intermediate phase in Bordetella pertussis during experimental respiratory infection.Semantic proximity Read ↗

A phase variant of Bordetella pertussis with a mutation in a new locus involved in the regulation of pertussis toxin and adenylate cyclase toxin expression.Semantic proximity Read ↗

Structural and genetic analysis of the bvg locus in Bordetella species.Semantic proximity Read ↗

Mutations in the linker region of BvgS abolish response to environmental signals for the regulation of the virulence factors in Bordetella pertussis.Semantic proximity Read ↗

Analysis of bvgR expression in Bordetella pertussis.Semantic proximity Read ↗

BvgR is important for virulence-related phenotypes in Bordetella bronchiseptica.Semantic proximity Read ↗

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