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Article

BvgR is important for virulence-related phenotypes in Bordetella bronchiseptica.

Microbiology spectrum - 5 Nov 2024

Gutierrez Maria de la Paz, Damron F Heath, Sisti Federico, Fernández Julieta

Abstract excerpt

Bordetella bronchiseptica is a pathogenic bacterium that causes respiratory infections in mammals. Adhesins, toxins, and secretion systems necessary for infection are regulated by the two-component system BvgAS. When the BvgAS system is inactive, there is no transcription of virulence-activated genes, and virulence-repressed genes (vrg) are expressed. The regulation of some vrgs in B. bronchiseptica is dependent...

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Identifiers

PMID: 39365045
DOI: 10.1128/spectrum.00794-24
PMCID: PMC11537037

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