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Article

Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine.

Infection and immunity - 1 Mar 2012

Nicholson Tracy L, Brockmeier Susan L, Loving Crystal L, Register Karen B, Kehrli Marcus E, Stibitz Scott E, Shore Sarah M

Abstract excerpt

The majority of virulence gene expression in Bordetella is regulated by a two-component sensory transduction system encoded by the bvg locus. In response to environmental cues, the BvgAS regulatory system controls expression of a spectrum of phenotypic phases, transitioning between a virulent (Bvg(+)) phase and a nonvirulent (Bvg(-)) phase, a process referred to as phenotypic modulation. We hypothesized that the...

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Identifiers

PMID: 22158743
DOI: 10.1128/IAI.06016-11
PMCID: PMC3294661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine.PMID 22158743Read ↗

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