Article
Analysis of bvgR expression in Bordetella pertussis.
Journal of bacteriology - 1 Dec 2003
Merkel Tod J, Boucher Philip E, Stibitz Scott, Grippe Vanessa K
Abstract excerpt
Bordetella pertussis, the causative agent of whooping cough, produces a wide array of factors that are associated with its ability to cause disease. The expression and regulation of these virulence factors are dependent upon the bvg locus, which encodes three proteins: BvgA, a 23-kDa cytoplasmic protein; BvgS, a 135-kDa transmembrane protein; and BvgR, a 32-kDa protein. It is hypothesized that BvgS responds to...
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