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Article

Evaluation of the role of the Bvg intermediate phase in Bordetella pertussis during experimental respiratory infection.

Infection and immunity - 1 Feb 2005

Vergara-Irigaray Nuria, Chávarri-Martínez Alberto, Rodríguez-Cuesta Juan, Miller Jeff F, Cotter Peggy A, Martínez de Tejada Guillermo

Abstract excerpt

The BvgAS system of Bordetella pertussis was traditionally considered to mediate a transition between two phenotypic phases (Bvg(+) and Bvg(-)) in response to environmental signals. We characterized a third state, the intermediate (Bvg(i)) phase, which can be induced by introducing a 1-bp substitution into bvgS (the bvgS-I1 mutation) or by growing B. pertussis under conditions intermediate between those leading...

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Identifiers

PMID: 15664913
DOI: 10.1128/IAI.73.2.748-760.2005
PMCID: PMC547029

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Source receipt: pubmed, retrieved 7 Sept 2026.

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