Article
Comparative analysis of the virulence control systems of Bordetella pertussis and Bordetella bronchiseptica.
Molecular microbiology - 1 Dec 1996
Martínez de Tejada G, Miller J F, Cotter P A
Abstract excerpt
Bordetella pertussis and Bordetella bronchiseptica contain nearly identical BvgAS signal-transduction systems that mediate a biphasic transition between virulent (Bvg+) and avirulent (Bvg-) phases. In the Bvg+ phase, the two species express a similar set of adhesins and toxins, and in both organisms the transition to the Bvg- phase occurs in response to the same environmental signals (low temperature or the...
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