Article
BvgAS-mediated signal transduction: analysis of phase-locked regulatory mutants of Bordetella bronchiseptica in a rabbit model.
Infection and immunity - 1 Aug 1994
Cotter P A, Miller J F
Abstract excerpt
Members of the Bordetella genus alternate between two distinct phenotypic phases in response to changes in their environment. This switch, termed phenotypic modulation, is mediated by the BvgAS sensory transduction system. We developed an animal model based on the interaction of Bordetella bronchiseptica with one of its natural hosts, the rabbit. To investigate the importance of BvgAS signal transduction, we...
Topics
- Animals
- Antibodies, Bacterial
- Bacterial Proteins
- Bordetella Infections
- Bordetella bronchiseptica
- Disease Models, Animal
- Enzyme-Linked Immunosorbent Assay
- Female
- Lung
- Mutation
- Rabbits
