Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure and biology of complement protein C3, a connecting link between innate and acquired immunity

1 Apr 2001

Abstract excerpt

Summary: Complement protein C3 is a central molecule in the complement system whose activation is essential for all the important functions performed by this system. After four decades of research it is now well established that C3 functions like a double‐edged sword: on the one hand it promotes phagocytosis, supports local inflammatory responses against pathogens, and instructs the adaptive immune response to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Erythrocyte Function and Pathophysiology
Share to Galectins and Cancer Biology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11414361
DOI: 10.1034/j.1600-065x.2001.1800103.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure and biology of complement protein C3, a connecting link between innate and acquired immunityPMID 11414361Read ↗

Structures of complement component C3 provide insights into the function and evolution of immunitySemantic proximity Read ↗

The versatile functions of complement C3‐derived ligandsSemantic proximity Read ↗

Complement C4, Infections, and Autoimmune DiseasesSemantic proximity Read ↗

Clinical Aspects and Molecular Basis of Primary Deficiencies of Complement Component C3 and its Regulatory Proteins Factor I and Factor HSemantic proximity Read ↗

Complement activation, regulation, and molecular basis for complement‐related diseasesSemantic proximity Read ↗

Structural Immunology of Complement Receptors 3 and 4Semantic proximity Read ↗

C3d of complement as a molecular adjuvant: Bridging innate and acquired immunitySemantic proximity Read ↗

Complement C3 and its polymorphism: biological and clinical consequences.Semantic proximity Read ↗

Complement dysregulation and disease: from genes and proteins to diagnostics and drugs.Semantic proximity Read ↗

The complement system: an evolution in progressSemantic proximity Read ↗

Structural biology of complement receptorsSemantic proximity Read ↗

New insights into the immune functions of complementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.