Article
Polymorphism of the beta2-adrenoceptor and the response to long-term beta2-agonist therapy in asthma.
The European respiratory journal - 1 Mar 1998
Hancox R J, Sears M R, Taylor D R
Abstract excerpt
Polymorphisms affecting amino acids 16 and 27 of the beta2-adrenoceptor alter receptor regulation in vitro. Whether these polymorphisms alter the response to beta2-agonist therapy in asthma is unknown. In a previous study of 64 asthmatics, most experienced a deterioration in asthma control during...
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