Article
Biallelic expression of all four IGF-II promoters and its association with increased methylation of H19 gene in human brain.
Brain research - 11 May 1998
Zhan S, Zhang L, Van M, Young C, Helman L J
Abstract excerpt
The human IGF-II gene is maternally imprinted in all tissues except adult liver and the choroid plexus/leptomeninges of the central nervous system where IGF-II is biallelically expressed. In human liver, it has recently been reported that this biallelic expression only involves the promoter P1 while the promoters P2-P4 direct IGF-II transcription monoallelically. To explore whether or not biallelic expression of...
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