Article
Differential biallelic activation of three insulin-like growth factor II promoters in the mouse central nervous system.
Molecular endocrinology (Baltimore, Md.) - 1 May 1995
Hu J F, Vu T H, Hoffman A R
Abstract excerpt
Imprinting of the insulin-like growth factor II gene (IGF-II) is conserved in human, rat, and mouse. In human liver and chondrocytes, IGF-II transcripts from promoter hP1 are always derived from both parental alleles, while transcripts from promoters hP2-hP4 are from one parental allele. To examine the promoter-specific imprinting pattern of mouse IGF-II, we examined IGF-II expression in F1 generation mice...
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