Article
Differential biallelic activation of three insulin-like growth factor II promoters in the mouse central nervous system.
Molecular endocrinology (Baltimore, Md.) - 1 May 1995
Hu J F, Vu T H, Hoffman A R
Abstract excerpt
Imprinting of the insulin-like growth factor II gene (IGF-II) is conserved in human, rat, and mouse. In human liver and chondrocytes, IGF-II transcripts from promoter hP1 are always derived from both parental alleles, while transcripts from promoters hP2-hP4 are from one parental allele. To exami...
Topics
- Alleles
- Animals
- Base Sequence
- Central Nervous System
- Female
- Gene Expression Regulation
- Genes, Reporter
- Insulin-Like Growth Factor II
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred Strains
- Molecular Sequence Data
- Organ Specificity
- Pedigree
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Transcription, Genetic