Promoter-specific insulin-like growth factor 2 gene imprinting in human fetal liver and hepatoblastoma.

doi:10.1002/(SICI)1096-9896(199805)185:1<91::AID-PATH44>3.0.CO;2-K

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Article

Promoter-specific insulin-like growth factor 2 gene imprinting in human fetal liver and hepatoblastoma.

The Journal of pathology - 1 May 1998

Yun K, Jinno Y, Sohda T, Niikawa N, Ikeda T

Abstract excerpt

Insulin-like growth factor 2 (IGF2) gene imprinting has been demonstrated to be promoter-specific, in that expression from the P1 promoter is biallelic whereas that from the P2-P4 promoters is monoallelic. In the present study, in order to investigate IGF2 gene imprinting status at the cellular l...

Topics

Alleles
Child
Genomic Imprinting
Genotype
Hepatoblastoma
Humans
In Situ Hybridization
Insulin-Like Growth Factor II
Liver
Liver Neoplasms
Polymerase Chain Reaction
Promoter Regions, Genetic
RNA, Messenger

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