Article
Promoter-specific insulin-like growth factor 2 gene imprinting in human fetal liver and hepatoblastoma.
The Journal of pathology - 1 May 1998
Yun K, Jinno Y, Sohda T, Niikawa N, Ikeda T
Abstract excerpt
Insulin-like growth factor 2 (IGF2) gene imprinting has been demonstrated to be promoter-specific, in that expression from the P1 promoter is biallelic whereas that from the P2-P4 promoters is monoallelic. In the present study, in order to investigate IGF2 gene imprinting status at the cellular level, allelic analysis was performed of IGF2 gene expression transcribed from the P1 and P3 promoters, using reverse...
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