Article
Pathology of sporadic breast tumors with LOH at the BRCA1 locus: correlation with histopathological features specific to familial BRCA1 tumors and absence of microsatellite instability.
International journal of oncology - 1 Jun 1998
Vaurs-Barriere C, Vidal V, Penault-Llorca F, Kwiatkowski F, Maugard C, Bignon Y
Abstract excerpt
To investigate the coordinated occurrence of loss of heterozygosity (LOH) at the BRCA1 locus and microsatellite instability (MI) in sporadic breast carcinomas, 56 tumors were analysed for both genetic alterations. The comparison of clinicopathological features with the obtained data revealed that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.