Protein kinase C and its isoforms in human breast cancer cells: relationship to the invasive phenotype.

doi:10.3892/ijo.12.6.1349

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Article

Protein kinase C and its isoforms in human breast cancer cells: relationship to the invasive phenotype.

International journal of oncology - 1 Jun 1998

Morse-Gaudio M, Connolly J M, Rose D P

Abstract excerpt

Total protein kinase C (PKC) activity and the expression of 9 isoforms were determined in the estrogen receptor (ER) positive MCF-7 human breast cancer cell line, this line transfected to overexpress either PKC-á or erbB2, and in 3 ER negative breast cancer cell lines. Relationships were sought b...

Topics

Blotting, Western
Breast Neoplasms
Cadherins
Cytoskeletal Proteins
Humans
Isoenzymes
Neoplasm Invasiveness
Phenotype
Protein Kinase C
Tumor Cells, Cultured
Urokinase-Type Plasminogen Activator
Vimentin
alpha Catenin

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