Article
The complexities of PKCα signaling in cancer.
Advances in biological regulation - 1 May 2021
Black Adrian R, Black Jennifer D
Abstract excerpt
Protein kinase C α (PKCα) is a ubiquitously expressed member of the PKC family of serine/threonine kinases with diverse functions in normal and neoplastic cells. Early studies identified anti-proliferative and differentiation-inducing functions for PKCα in some normal tissues (e.g., regenerating epithelia) and pro-proliferative effects in others (e.g., cells of the hematopoietic system, smooth muscle cells)....
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