The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance.

doi:10.1016/s0026-0495(97)90054-8

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Article

The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance.

Metabolism: clinical and experimental - 1 Apr 1997

Chiu K C, McCarthy J E

Abstract excerpt

Plasma angiotensin I-converting enzyme (ACE) levels are genetically predetermined and are correlated with a deletion (D) insertion (I) polymorphism at the ACE gene locus. A subset of diabetic patients are noted to have elevated ACE levels. Treatment with ACE inhibitors has been shown to improve i...

Topics

Alleles
Blood Glucose
Glucose Tolerance Test
Humans
Insulin
Insulin Resistance
Peptidyl-Dipeptidase A
Polymorphism, Genetic

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