Article
The yeast MER2 gene is required for chromosome synapsis and the initiation of meiotic recombination.
Genetics - 1 Sept 1995
Rockmill B, Engebrecht J A, Scherthan H, Loidl J, Roeder G S
Abstract excerpt
Mutation of the MER2 gene of Saccharomyces cerevisiae confers meiotic lethality. To gain insight into the function of the Mer2 protein, we have carried out a detailed characterization of the mer2 null mutant. Genetic analysis indicates that mer2 completely eliminates meiotic interchromosomal gene conversion and crossing over. In addition, mer2 abolishes intrachromosomal meiotic recombination, both in the...
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